Toothpaste, ranked by PFAS grade

15 products graded from Bad to Excellent, best-graded first. 15 grade Good or better and are worth buying.

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The best non-toxic toothpaste, ranked by grade

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Buyer’s guide

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Worth buying Good or Excellent, best-graded first

COLGATE CAVITY PROTECTION TOOTHPASTE

Colgate

CAVITY PROTECTION TOOTHPASTE

aqueous gel with fluoride, silica, sorbitol, cellulose

PFAS Grade75Excellent
Overall Grade71Good
⚠️

Fluoride ingestion (systemic dose risk)

Limited concern

70

Minimal concern; toothpaste formulation has no inherent PFAS application drivers.

Starting grade for this product type

Colgate Whitening Gel Toothpaste

Colgate

Whitening Gel Toothpaste

Aqueous gel base with fluoride, silica, surfactants, glycerin

PFAS Grade75Excellent
Overall Grade57Good
⚠️

Fluoride (swallowing risk in children)

Moderate concern

45

Silica abrasive (enamel wear)

Limited concern

70
⚠️

Surfactant irritation (mouth/gum sensitivity)

Limited concern

70

Minimal PFAS concern; standard toothpaste with no known Teflon-family coating or water-repellent coating triggers.

Starting grade for this product type

Colgate Optic White Toothpaste

Colgate

Optic White Toothpaste

aqueous gel base with fluoride, silica, glycerin

PFAS Grade75Excellent
Overall Grade67Good
⚠️

Fluoride systemic toxicity (ingestion)

Limited concern

70
⚠️

Fragrance and flavor allergens

Limited concern

70

Minimal PFAS concern; standard toothpaste with no identified high-risk ingredients.

Starting grade for this product type

Sensodyne Cavity + Sensitivity Toothpaste

Sensodyne

Cavity + Sensitivity Toothpaste

Aqueous gel toothpaste, standard formulation

PFAS Grade75Excellent
Overall Grade61Good
⚠️

Fluoride toxicity (systemic, from ingestion)

Limited concern

70
⚠️

Sodium lauryl sulfate (SLS) irritation

Moderate concern

45

Minimal concern; no PFAS-prone additives in standard toothpaste, no brand disclosure.

Starting grade for this product type

Sensodyne Pronamel Toothpaste Gentle Whitening

Sensodyne

Pronamel Toothpaste Gentle Whitening

Aqueous gel base with calcium compounds and abrasives (silica/alumina); typical toothpaste formulation

PFAS Grade75Excellent
Overall Grade67Good
⚠️

Fluoride toxicity (systemic ingestion)

Limited concern

70
⚠️

Allergic contact dermatitis from flavorings or thickeners

Limited concern

70

Minimal concern; standard toothpaste with no known PFAS triggers, no explicit brand disclosure.

Starting grade for this product type

Sensodyne Repair and Protect Whitening Toothpaste

Sensodyne

Repair and Protect Whitening Toothpaste

aqueous gel toothpaste (typical glycerin, silica, sodium fluoride base)

PFAS Grade75Excellent
Overall Grade67Good
⚠️

Fluoride content

Limited concern

70
⚠️

Fragrance/flavor allergens

Limited concern

70

Lower PFAS concern for typical oral-use toothpaste; no known Teflon-family coating or water-repellent coating triggers.

Starting grade for this product type

Tom's of Maine Fluoride-Free Antiplaque Whitening Toothpaste

Tom's of Maine

Fluoride-Free Antiplaque Whitening Toothpaste

Glycerin, calcium carbonate, silica, natural flavoring, gum base (typical toothpaste formula)

PFAS Grade75Excellent
Overall Grade71Good
⚠️

Fragrance or flavoring allergens

Limited concern

70

Lower PFAS concern for a basic toothpaste; no Teflon-family coating or water-resistance coatings expected in standard oral care.

Starting grade for this product type

Tom's of Maine Fluoride-Free Antiplaque Whitening Natural Toothpaste (2 Pack)

Tom's of Maine

Fluoride-Free Antiplaque Whitening Natural Toothpaste (2 Pack)

toothpaste gel/paste (mineral, humectant, and natural abrasive base)

PFAS Grade75Excellent
Overall Grade67Good
🫧

Abrasive particle size and enamel wear

Limited concern

70
⚠️

Fragrance allergens and sensitizers

Limited concern

70

Lower concern; toothpaste formulations rarely require PFAS, but Tom's does not voluntarily disclose.

Starting grade for this product type

Tom's of Maine Antiplaque Whitening Toothpaste

Tom's of Maine

Antiplaque Whitening Toothpaste

water-based gel with sorbitol, hydrated silica, fluoride compound

PFAS Grade75Excellent
Overall Grade67Good
⚠️

Fluoride systemic toxicity (ingestion risk)

Limited concern

70
⚠️

Sorbitol digestive effect (minor ingestion)

Limited concern

70

Lower PFAS concern, toothpaste formula has no routine need for PFAS; skip if you want explicit assurance.

Starting grade for this product type

Crest Cavity Protection Toothpaste

Crest

Cavity Protection Toothpaste

aqueous gel/paste (fluoride, silica, glycerin, detergents)

PFAS Grade75Excellent
Overall Grade61Good
⚠️

Fluoride ingestion risk (primarily pediatric)

Moderate concern

45
⚠️

Sodium lauryl sulfate (SLS) sensitivity or allergic contact dermatitis

Limited concern

70

Lower concern, standard toothpaste with no known PFAS exposure pathway, but Crest has not publicly disclosed PFAS testing.

Starting grade for this product type

Crest Complete Scope Whitening Toothpaste

Crest

Complete Scope Whitening Toothpaste

Aqueous gel/paste with standard cosmetic additives

PFAS Grade75Excellent
Overall Grade53Good
⚠️

Sodium Fluoride (ingestion risk in children)

Limited concern

70
⚠️

Sodium Lauryl Sulfate (SLS) sensitivity

Limited concern

70

Abrasive particulate (silica) and enamel wear

Moderate concern

45
🎨

Artificial colorants and flavorings (allergen potential)

Limited concern

70

Lower PFAS concern for typical toothpaste; no evidence triggers alarm.

Starting grade for this product type

Crest 3D White Advanced Glamorous White Teeth Whitening Toothpaste

Crest

3D White Advanced Glamorous White Teeth Whitening Toothpaste

Aqueous toothpaste gel with fluoride active

PFAS Grade75Excellent
Overall Grade53Good
⚠️

Fluoride ingestion risk

Limited concern

70
🍳

Abrasive damage to enamel

Limited concern

70
⚠️

Fragrance allergens and irritants

Limited concern

70
⚠️

Sodium lauryl sulfate (SLS) detergent

Moderate concern

45

Lower PFAS concern; standard toothpaste formulation with no known Teflon-family coating coatings or DWFR treatments.

Starting grade for this product type

Crest Pro-Health Advanced Deep Clean Mint Toothpaste

Crest

Pro-Health Advanced Deep Clean Mint Toothpaste

Aqueous gel toothpaste base with typical cosmetic excipients

PFAS Grade75Excellent
Overall Grade67Good
⚠️

Fluoride ingestion (children under 3)

Limited concern

70
⚠️

Fragrance allergens (mint flavoring)

Limited concern

70

Lower concern, typical toothpaste formulation with no known PFAS-prone features; Crest has made no PFAS claims or disclosures.

Starting grade for this product type

Crest Clean Mint Pro-Health Toothpaste

Crest

Clean Mint Pro-Health Toothpaste

aqueous gel toothpaste base with standard cosmetic excipients

PFAS Grade75Excellent
Overall Grade71Good
⚠️

Fragrance allergens and irritants

Limited concern

70

Lower PFAS concern for typical toothpaste; no evidence of intentional PFAS use in oral care formulations.

Starting grade for this product type

Crest Complete Scope Outlast Ultra Toothpaste

Crest

Complete Scope Outlast Ultra Toothpaste

aqueous gel base with fluoride, silicas, polymers, surfactants

PFAS Grade75Excellent
Overall Grade71Good
⚠️

Flavor allergens (mint, cinnamaldehyde, other additives)

Limited concern

70

Lower concern, typical toothpaste formula with no known PFAS triggers, but brand discloses nothing.

Starting grade for this product type

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