The Best Non-Toxic Toothpaste of 2026
We scored 15 toothpaste products for PFAS forever chemicals and other hazards, then ranked them best-graded first. The top pick is COLGATE CAVITY PROTECTION TOOTHPASTE at 75/100. Every score below links to the full breakdown of what earned it.
0% of the 15 toothpaste products we scored fail our PFAS and toxin screen.
The best-scoring toothpaste for PFAS risk
- 1
Colgate
CAVITY PROTECTION TOOTHPASTE
aqueous gel with fluoride, silica, sorbitol, cellulose
PFAS Grade75ExcellentOverall Grade71Good⚠️70Fluoride ingestion (systemic dose risk)
Limited concern
Minimal concern; toothpaste formulation has no inherent PFAS application drivers.
⚠Starting grade for this product type
- 2
Colgate
Whitening Gel Toothpaste
Aqueous gel base with fluoride, silica, surfactants, glycerin
PFAS Grade75ExcellentOverall Grade57Good⚠️45Fluoride (swallowing risk in children)
Moderate concern
⏳70Silica abrasive (enamel wear)
Limited concern
⚠️70Surfactant irritation (mouth/gum sensitivity)
Limited concern
Minimal PFAS concern; standard toothpaste with no known Teflon-family coating or water-repellent coating triggers.
⚠Starting grade for this product type
- 3
Colgate
Optic White Toothpaste
aqueous gel base with fluoride, silica, glycerin
PFAS Grade75ExcellentOverall Grade67Good⚠️70Fluoride systemic toxicity (ingestion)
Limited concern
⚠️70Fragrance and flavor allergens
Limited concern
Minimal PFAS concern; standard toothpaste with no identified high-risk ingredients.
⚠Starting grade for this product type
- 4
Sensodyne
Cavity + Sensitivity Toothpaste
Aqueous gel toothpaste, standard formulation
PFAS Grade75ExcellentOverall Grade61Good⚠️70Fluoride toxicity (systemic, from ingestion)
Limited concern
⚠️45Sodium lauryl sulfate (SLS) irritation
Moderate concern
Minimal concern; no PFAS-prone additives in standard toothpaste, no brand disclosure.
⚠Starting grade for this product type
- 5
Sensodyne
Pronamel Toothpaste Gentle Whitening
Aqueous gel base with calcium compounds and abrasives (silica/alumina); typical toothpaste formulation
PFAS Grade75ExcellentOverall Grade67Good⚠️70Fluoride toxicity (systemic ingestion)
Limited concern
⚠️70Allergic contact dermatitis from flavorings or thickeners
Limited concern
Minimal concern; standard toothpaste with no known PFAS triggers, no explicit brand disclosure.
⚠Starting grade for this product type
- 6
Sensodyne
Repair and Protect Whitening Toothpaste
aqueous gel toothpaste (typical glycerin, silica, sodium fluoride base)
PFAS Grade75ExcellentOverall Grade67Good⚠️70Fluoride content
Limited concern
⚠️70Fragrance/flavor allergens
Limited concern
Lower PFAS concern for typical oral-use toothpaste; no known Teflon-family coating or water-repellent coating triggers.
⚠Starting grade for this product type
- 7
Tom's of Maine
Fluoride-Free Antiplaque Whitening Toothpaste
Glycerin, calcium carbonate, silica, natural flavoring, gum base (typical toothpaste formula)
PFAS Grade75ExcellentOverall Grade71Good⚠️70Fragrance or flavoring allergens
Limited concern
Lower PFAS concern for a basic toothpaste; no Teflon-family coating or water-resistance coatings expected in standard oral care.
⚠Starting grade for this product type
- 8
Tom's of Maine
Fluoride-Free Antiplaque Whitening Natural Toothpaste (2 Pack)
toothpaste gel/paste (mineral, humectant, and natural abrasive base)
PFAS Grade75ExcellentOverall Grade67Good🫧70Abrasive particle size and enamel wear
Limited concern
⚠️70Fragrance allergens and sensitizers
Limited concern
Lower concern; toothpaste formulations rarely require PFAS, but Tom's does not voluntarily disclose.
⚠Starting grade for this product type
Questions people ask about toothpaste
Every toothpaste that passes, side by side
Sorted by score. A higher score means lower PFAS risk.
| # | Toothpaste | Score | Rating | Made of |
|---|---|---|---|---|
| 1 | COLGATE CAVITY PROTECTION TOOTHPASTE | 75 | Excellent | aqueous gel with fluoride, silica, sorbitol, cellulose |
| 2 | Colgate Whitening Gel Toothpaste | 75 | Excellent | Aqueous gel base with fluoride, silica, surfactants, glycerin |
| 3 | Colgate Optic White Toothpaste | 75 | Excellent | aqueous gel base with fluoride, silica, glycerin |
| 4 | Sensodyne Cavity + Sensitivity Toothpaste | 75 | Excellent | Aqueous gel toothpaste, standard formulation |
| 5 | Sensodyne Pronamel Toothpaste Gentle Whitening | 75 | Excellent | Aqueous gel base with calcium compounds and abrasives (silica/alumina); typical toothpaste formulation |
| 6 | Sensodyne Repair and Protect Whitening Toothpaste | 75 | Excellent | aqueous gel toothpaste (typical glycerin, silica, sodium fluoride base) |
| 7 | Tom's of Maine Fluoride-Free Antiplaque Whitening Toothpaste | 75 | Excellent | Glycerin, calcium carbonate, silica, natural flavoring, gum base (typical toothpaste formula) |
| 8 | Tom's of Maine Fluoride-Free Antiplaque Whitening Natural Toothpaste (2 Pack) | 75 | Excellent | toothpaste gel/paste (mineral, humectant, and natural abrasive base) |
The toothpaste we would skip
Lowest scoring in this category, worst first.
Colgate
CAVITY PROTECTION TOOTHPASTE
aqueous gel with fluoride, silica, sorbitol, cellulose
Fluoride ingestion (systemic dose risk)
Limited concern
Minimal concern; toothpaste formulation has no inherent PFAS application drivers.
⚠Starting grade for this product type
Colgate
Whitening Gel Toothpaste
Aqueous gel base with fluoride, silica, surfactants, glycerin
Fluoride (swallowing risk in children)
Moderate concern
Silica abrasive (enamel wear)
Limited concern
Surfactant irritation (mouth/gum sensitivity)
Limited concern
Minimal PFAS concern; standard toothpaste with no known Teflon-family coating or water-repellent coating triggers.
⚠Starting grade for this product type
Colgate
Optic White Toothpaste
aqueous gel base with fluoride, silica, glycerin
Fluoride systemic toxicity (ingestion)
Limited concern
Fragrance and flavor allergens
Limited concern
Minimal PFAS concern; standard toothpaste with no identified high-risk ingredients.
⚠Starting grade for this product type
What we check on toothpaste
- Confirmed PFAS, PTFE or fluoropolymer content, which is the heaviest penalty we apply.
- Stain, water or grease resistant treatments, which usually mean fluorinated chemistry.
- Whether the brand discloses what is in the product, or stays silent behind a “clean” claim.
- Independent lab results and certifications where they exist.
Full point-by-point rubric on the methodology page.
The toothpaste brands that will not say
4 of the brands here publish nothing about PFAS at all. Silence is not evidence of harm, but it is why none of them score well on disclosure.
Colgate, Crest, Sensodyne, Tom's of Maine.
Common questions about PFAS in toothpaste
Is toothpaste PFAS free?
Mostly not. Of the 15 toothpaste we have scored, 0% fail our PFAS and toxin screen, which leaves 15 that pass. The highest scoring is COLGATE CAVITY PROTECTION TOOTHPASTE at 75 out of 100. The lowest is COLGATE CAVITY PROTECTION TOOTHPASTE at 75.
Which toothpaste grades best for PFAS?
COLGATE CAVITY PROTECTION TOOTHPASTE, at 75 out of 100, which we band as Excellent. It is aqueous gel with fluoride, silica, sorbitol, cellulose. The runner up is Colgate Whitening Gel Toothpaste at 75.
Which toothpaste should I avoid?
The three lowest scoring we hold are COLGATE CAVITY PROTECTION TOOTHPASTE at 75, Colgate Whitening Gel Toothpaste at 75, Colgate Optic White Toothpaste at 75. The problem with the first is that the main material recorded for this product is not one associated with PFAS.
Which toothpaste brands will not say whether they use PFAS?
4 of the brands we scored in this category publish nothing about PFAS at all, including Colgate, Crest, Sensodyne, Tom's of Maine. Silence is not evidence of harm, but it is the reason those brands cannot score well on disclosure.
Do you lab test toothpaste?
No. We score from published ingredient lists, materials, certifications, disclosures and third party lab results where they exist. Where a product has been independently tested we use that result and say so.
More beauty and personal care categories we have graded
Same rubric, same scale. These are the categories closest to toothpaste.
- Best non-toxic deodorant265 graded
- Best non-toxic lip balm240 graded
- Best non-toxic incontinence pads & protection225 graded
- Best non-toxic sunscreen201 graded
- Best non-toxic menstrual cups15 graded
- Best non-toxic office chairs15 graded
- Best non-toxic shaving cream15 graded
- Best non-toxic hair styling products15 graded
Get the graded list, free
The products we score each week, and the best-graded alternative in every category.
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We also wrote this up at length. PFAS in Toothpaste, and Why This Is Not the Category to Worry About
Want to filter the whole category yourself? Browse all 15 toothpaste.