Clinique Smart Clinical Repair Collagen + PDRN Cream Moisturizer
Cosmetic cream with lower concern; Clinique makes no PFAS disclosures.
Face cream with common moisturizing ingredients like collagen and glycerin. No published PFAS claims or lab testing; standard cosmetic formulation carries lower PFAS risk than water-resistant or treated products.
We flunk more products than we pass. This one earned its grade. How we grade
Material
water, glycerin, collagen, PDRN, emollients
Lab data
No public lab test
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What Clinique Smart Clinical Repair Moisturizer is made of, ingredients and materials
This moisturizer is a water-glycerin emulsion base with collagen (a protein humectant) and PDRN (polydeoxyribonucleotide, a marine-derived cell-signaling ingredient). The formula contains common emollients and preservatives typical of prestige cosmetics. None of these classes, hydrolyzed protein, nucleotides, or standard emulsifiers in leave-on creams, carry established contamination or toxicity concerns at cosmetic-use concentrations.
What’s concerning
Category baseline
The starting point for this type of product, before anything specific to this product is counted.
No PFAS disclosure
No public statement from the brand about PFAS in this product.
1,4-dioxane (solvent and manufacturing byproduct)
Water-based emulsified creams can contain trace 1,4-dioxane as a manufacturing byproduct if ethoxylated surfactants are used and not fully purged. Clinique does not publish residual solvent testing for this product; the risk is low but not independently verified.
What’s reassuring
Base material not linked to PFAS
The main material recorded for this product is not one associated with PFAS.
Fragrance allergens and sensitizers
Clinique Smart Clinical Repair does not list fragrance or essential oils in its disclosed ingredients. No fragrance-related adverse events or recalls are on record for this specific product.
Formaldehyde / VOCs
The preservative system in this formula does not include imidazolidinyl urea, dmdm hydantoin, or other known releasers based on available ingredient disclosures. No regulatory alerts exist for this product.
Source, ATSDR ↗Heavy metals
This is a colorless to pale cream with no added pigments, mica, or mineral clays listed. Collagen and PDRN are protein and nucleotide-based and are not vehicles for cadmium, lead, or antimony contamination at cosmetic scale.
Source, FDA ↗Talc contamination
Talc is not listed in the ingredient declaration. The texture is provided by glycerin and emulsifiers, not mineral powders.
How is this PFAS grade calculated?
The brand's record and disclosure
Clinique (Estée Lauder Companies) does not publicly disclose PFAS content or commit to PFAS-free formulations across its portfolio. The brand has not faced documented recalls or regulatory actions specific to heavy metals, formaldehyde, talc, or 1,4-dioxane in recent moisturizers. Clinique follows FDA and EU cosmetics compliance but does not volunteer third-party safety testing data.
How it compares in its category
This product sits in the mid-to-premium moisturizer segment. Its water-forward, protein-based formula is typical of anti-aging creams marketed to dermatology channels. Compared to mineral oil-heavy or fragrance-heavy alternatives, the reliance on collagen and PDRN rather than synthetic actives lowers exposure to known allergens or irritants, though efficacy claims remain marketing-based.
If you buy it
Store at room temperature away from direct heat or sunlight; cream formulas can degrade if left in hot vehicles or near radiators. No special maintenance is required. Discontinue use if redness, stinging, or rash develops; patch-test on the inner arm first if you have sensitive skin. Shelf life is typically 12-24 months from purchase; discard if separation, odor change, or mold appear.
What is not known about PFAS in this product?
- Basis
- Model estimate, 72% confidence, not a lab result
- Lab test
- None on record for this exact product
- Brand statement
- Clinique has made a specific claim
Formulations change between production runs, so check the current label. How we grade.
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3 hazards checked on this product, all on its full breakdown.
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