The Best Non-Toxic Cleaning Wipes of 2026

We scored 14 cleaning wipes for PFAS forever chemicals and other hazards, then ranked them safest first. The top pick is Seventh Generation Disinfecting Wipes Disinfecting Wipes Seventh Generation at 100/100. Every score below links to the full breakdown of what earned it.

How to read these scores. PFAS Authority is a scoring system, not a laboratory. We do not test products ourselves. Each grade is a model-based assessment built from published ingredient lists, materials, certifications, brand disclosures, recalls and third-party lab results where they exist. Read the full rubric to see exactly what adds and removes points.
0% of the 14 cleaning wipes we scored fail our PFAS and toxin screen.
PFAS Authority, September 2026. Free to cite with a link. See the full dataset.

The safest PFAS-free cleaning wipes we have scored

  1. 1
    Disinfecting Wipes Seventh Generation

    Seventh Generation Disinfecting Wipes

    Disinfecting Wipes Seventh Generation

    nonwoven fabric (polypropylene/polyester blend), quaternary ammonium disinfectant

    PFAS Grade100Excellent
    Overall Grade92Excellent
    ⚠️

    Quaternary ammonium (quat) skin irritation

    Limited concern

    70
    ⚠️

    Respiratory irritation from quat aerosol

    Limited concern

    70

    Low risk, Seventh Generation's transparent stance and third-party certifications support a safer choice.

    ✓ MADE SAFE Certified✓ EPA Safer Choice

    ✓Verified PFAS-free by a third party

    Why this gradeBuy
  2. 2
    Seventh Generation Multi Wipes

    Seventh Generation

    Multi Wipes

    nonwoven fabric blend (cellulose/synthetic fibers)

    PFAS Grade85Excellent
    Overall Grade77Excellent
    ⚠️

    Skin irritation from quaternary ammonium compounds

    Limited concern

    70
    ⚠️

    Eye irritation

    Limited concern

    70

    Low risk, no known PFAS need in this category; brand discloses nothing.

    ⚠Brand says nothing about PFAS

    Why this gradeBuy
  3. 3
    Seventh Generation Botanical Disinfecting Wipes 7 x 8 70 Count (6/Carton)

    Seventh Generation

    Botanical Disinfecting Wipes 7 x 8 70 Count (6/Carton)

    nonwoven fabric wipes (likely polypropylene or cellulose blend)

    PFAS Grade85Excellent
    Overall Grade73Good
    ⚠️

    Fragrance allergens and skin irritant potential

    Limited concern

    70
    🫧

    Nonwoven substrate microfiber shedding

    Limited concern

    70
    ⚠️

    Respiratory irritant from aerosolized spray during use

    Limited concern

    70

    Low risk, no known PFAS trigger; brand does not explicitly disclose PFAS absence.

    ⚠Brand says nothing about PFAS

    Why this gradeBuy
  4. 4
    Clorox Disinfecting Cleaning Wipes Variety Pack, Bleach Free, Fresh Scent and Crisp Lemon, 35 Count Each, Pack of 3, Size: 105 ct

    Clorox

    Disinfecting Cleaning Wipes Variety Pack, Bleach Free, Fresh Scent and Crisp Lemon, 35 Count Each, Pack of 3, Size: 105 ct

    nonwoven fabric wipes (polyester/polypropylene blend)

    PFAS Grade85Excellent
    Overall Grade69Good
    ⚠️

    Quat (quaternary ammonium) residue on food-contact surfaces

    Limited concern

    70
    ⚠️

    Fragrance allergens in 'Fresh Scent' and 'Crisp Lemon' formulations

    Limited concern

    70
    🫧

    Nonwoven fiber shedding and microfiber dispersal

    Limited concern

    70
    ⚠️

    Skin irritation from quat solution with prolonged contact

    Limited concern

    70

    Low concern, though Clorox offers no transparency on PFAS.

    ⚠Brand says nothing about PFAS

    Why this gradeBuy
  5. 5
    Clorox Bleach Germicidal Wipes 12 x 12

    Clorox

    Bleach Germicidal Wipes 12 x 12

    Nonwoven polypropylene wipe with sodium hypochlorite bleach solution

    PFAS Grade85Excellent
    Overall Grade67Good
    💨

    Sodium hypochlorite reactivity and inhalation risk

    Limited concern

    70
    ⚠️

    Chemical reaction with ammonia or acids

    Moderate concern

    45
    ⚠️

    Skin sensitization or irritation from bleach or wipe substrate

    Limited concern

    70

    Low concern, bleach wipes skip typical PFAS triggers, though Clorox hasn't disclosed PFAS status.

    ⚠Brand says nothing about PFAS

    Why this gradeBuy
  6. 6
    Clorox Disinfecting Wipes

    Clorox Disinfecting Wipes

    Clorox Disinfecting Wipes

    Nonwoven polypropylene substrate with disinfectant surfactants

    PFAS Grade75Excellent
    Overall Grade43Poor
    💨

    Sodium hypochlorite (bleach) irritation and inhalation

    Moderate concern

    45
    🏷️

    Undisclosed surfactant composition

    Limited concern

    70
    ⏳

    Polypropylene substrate degradation over time

    Limited concern

    70
    ⚠️

    Residual bleach on food-contact surfaces

    Moderate concern

    45

    Skip until Clorox discloses PFAS status, wipes are not an essential purchase.

    ⚠Brand says nothing about PFAS

    Why this gradeBuy
  7. 7
    Disinfecting Wipes Lysol

    Lysol Disinfecting Wipes

    Disinfecting Wipes Lysol

    nonwoven fabric blend (polypropylene/polyester base), aqueous disinfectant formulation

    PFAS Grade75Excellent
    Overall Grade57Good
    💨

    Quaternary ammonium compound (quat) inhalation and skin sensitization

    Limited concern

    70
    🏷️

    Incomplete formula disclosure

    Moderate concern

    45
    🫧

    Microplastic shedding from nonwoven substrate

    Limited concern

    70

    Silent on PFAS; formula opacity warrants caution despite no obvious fluorinated triggers.

    ⚠Brand says nothing about PFAS

    Why this gradeBuy
  8. 8
    Lysol Brand New Day Disinfecting Wipes

    Lysol Disinfecting Wipes

    Lysol Brand New Day Disinfecting Wipes

    nonwoven fabric (cellulose/polypropylene blend), aqueous disinfectant solution

    PFAS Grade75Excellent
    Overall Grade53Good
    ⚠️

    Quaternary ammonium compound (quat) sensitization

    Limited concern

    70
    ⚠️

    Preservative or fragrance allergens

    Limited concern

    70
    ⛏️

    Aqueous liquid leachate into skin or eyes on contact

    Moderate concern

    45
    ♾️

    PFAS

    Limited concern

    70

    Disinfectant wipes have no known reason to contain PFAS; Lysol does not disclose coating details.

    ⚠Brand says nothing about PFAS

    Why this gradeBuy

Every cleaning wipes that passes, side by side

Sorted by score. Higher is safer. Scored against 2 hazards that apply to this category.

#Cleaning WipesScoreRatingMade of
1Seventh Generation Disinfecting Wipes Disinfecting Wipes Seventh Generation100Excellentnonwoven fabric (polypropylene/polyester blend), quaternary ammonium disinfectant
2Seventh Generation Seventh Generation Multi Wipes85Excellentnonwoven fabric blend (cellulose/synthetic fibers)
3Seventh Generation Seventh Generation Botanical Disinfecting Wipes 7 x 8 70 Count (6/Carton)85Excellentnonwoven fabric wipes (likely polypropylene or cellulose blend)
4Clorox Clorox Disinfecting Cleaning Wipes Variety Pack, Bleach Free, Fresh Scent and Crisp Lemon, 35 Count Each, Pack of 3, Size: 105 ct85Excellentnonwoven fabric wipes (polyester/polypropylene blend)
5Clorox Clorox Bleach Germicidal Wipes 12 x 1285ExcellentNonwoven polypropylene wipe with sodium hypochlorite bleach solution
6Clorox Disinfecting Wipes Clorox Disinfecting Wipes75ExcellentNonwoven polypropylene substrate with disinfectant surfactants
7Lysol Disinfecting Wipes Disinfecting Wipes Lysol75Excellentnonwoven fabric blend (polypropylene/polyester base), aqueous disinfectant formulation
8Lysol Disinfecting Wipes Lysol Brand New Day Disinfecting Wipes75Excellentnonwoven fabric (cellulose/polypropylene blend), aqueous disinfectant solution

The cleaning wipes we would skip

Lowest scoring in this category, worst first.

Clorox Disinfecting Wipes

Clorox Disinfecting Wipes

Clorox Disinfecting Wipes

Nonwoven polypropylene substrate with disinfectant surfactants

PFAS Grade75Excellent
Overall Grade43Poor
💨

Sodium hypochlorite (bleach) irritation and inhalation

Moderate concern

45
🏷️

Undisclosed surfactant composition

Limited concern

70
⏳

Polypropylene substrate degradation over time

Limited concern

70
⚠️

Residual bleach on food-contact surfaces

Moderate concern

45

Skip until Clorox discloses PFAS status, wipes are not an essential purchase.

⚠Brand says nothing about PFAS

Why this gradeBuy
Disinfecting Wipes Lysol

Lysol Disinfecting Wipes

Disinfecting Wipes Lysol

nonwoven fabric blend (polypropylene/polyester base), aqueous disinfectant formulation

PFAS Grade75Excellent
Overall Grade57Good
💨

Quaternary ammonium compound (quat) inhalation and skin sensitization

Limited concern

70
🏷️

Incomplete formula disclosure

Moderate concern

45
🫧

Microplastic shedding from nonwoven substrate

Limited concern

70

Silent on PFAS; formula opacity warrants caution despite no obvious fluorinated triggers.

⚠Brand says nothing about PFAS

Why this gradeBuy
Lysol Brand New Day Disinfecting Wipes

Lysol Disinfecting Wipes

Lysol Brand New Day Disinfecting Wipes

nonwoven fabric (cellulose/polypropylene blend), aqueous disinfectant solution

PFAS Grade75Excellent
Overall Grade53Good
⚠️

Quaternary ammonium compound (quat) sensitization

Limited concern

70
⚠️

Preservative or fragrance allergens

Limited concern

70
⛏️

Aqueous liquid leachate into skin or eyes on contact

Moderate concern

45
♾️

PFAS

Limited concern

70

Disinfectant wipes have no known reason to contain PFAS; Lysol does not disclose coating details.

⚠Brand says nothing about PFAS

Why this gradeBuy

What we check on cleaning wipes

  • Phthalates. Plastic softeners studied for endocrine effects. ATSDR
  • Endocrine disruptors. Chemicals that interfere with the body’s hormone system. NIEHS

Full point-by-point rubric on the methodology page.

The cleaning wipes brands that will not say

4 of the brands here publish nothing about PFAS at all. Silence is not evidence of harm, but it is why none of them score well on disclosure.

Clorox, Clorox Disinfecting Wipes, Lysol Disinfecting Wipes, Seventh Generation.

Common questions about PFAS-free cleaning wipes

Is cleaning wipes PFAS free?

Mostly not. Of the 14 cleaning wipes we have scored, 0% fail our PFAS and toxin screen, which leaves 14 that pass. The highest scoring is Seventh Generation Disinfecting Wipes Disinfecting Wipes Seventh Generation at 100 out of 100. The lowest is Clorox Disinfecting Wipes Clorox Disinfecting Wipes at 75.

What is the safest cleaning wipes you have scored?

Seventh Generation Disinfecting Wipes Disinfecting Wipes Seventh Generation, at 100 out of 100, which we band as Excellent. It is nonwoven fabric (polypropylene/polyester blend), quaternary ammonium disinfectant. The runner up is Seventh Generation Seventh Generation Multi Wipes at 85.

Which cleaning wipes should I avoid?

The three lowest scoring we hold are Clorox Disinfecting Wipes Clorox Disinfecting Wipes at 75, Lysol Disinfecting Wipes Disinfecting Wipes Lysol at 75, Lysol Disinfecting Wipes Lysol Brand New Day Disinfecting Wipes at 75. The problem with the first is that skip until Clorox discloses PFAS status, wipes are not an essential purchase.

How can you tell if cleaning wipes contain PFAS?

In this category we check for phthalates, endocrine disruptors. Plastic softeners studied for endocrine effects. Language like stain resistant, water repellent or easy release usually means fluorinated chemistry even when PFAS is never printed on the box.

Which cleaning wipes brands will not say whether they use PFAS?

4 of the brands we scored in this category publish nothing about PFAS at all, including Clorox, Clorox Disinfecting Wipes, Lysol Disinfecting Wipes, Seventh Generation. Silence is not evidence of harm, but it is the reason those brands cannot score well on disclosure.

Do you lab test cleaning wipes?

No. We score from published ingredient lists, materials, certifications, disclosures and third party lab results where they exist. Where a product has been independently tested we use that result and say so.

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