Non-Toxic Hand Sanitizer, ranked by PFAS grade

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Top-graded picks in the categories readers replace first, every one scored on the same rubric.

  • polypropylene filter housing, carbon/sediment cartridge
  • We found no PFAS statement from the brand
  • Bacterial growth in spent cartridges

3 hazards checked on this product, all on its full breakdown.

  • RO membrane, carbon filters, stainless steel housing
  • We found no PFAS statement from the brand
  • Bacterial and microbial growth in housing and filters

4 hazards checked on this product, all on its full breakdown.

Avocado Vegan Mattress

Avocado

Vegan Mattress

100ExcellentPFAS grade
✓ MADE SAFE Certified✓ Global Organic Textile Standard (GOTS)
  • organic cotton, natural latex, coconut coir, recycled steel coils
  • The brand calls it PFAS-free, which we have not verified
  • Heavy metals

2 hazards checked on this product, all on its full breakdown.

What we found
All 15 hand sanitizer products PFAS Authority has graded reach its 70 point pass mark for PFAS and other toxins, as of October 2026. The highest graded is Dettol Instant Hand Sanitizer 50ml at 75 out of 100.

The full ranking is below, best-graded first, with every score linking to the evidence behind it.

Is hand sanitizer safe?

15 of the 15 hand sanitizer products we graded come back low-concern on our screen and 0 do not. Our grades are model-based assessments built from published materials, ingredient lists, certifications and brand disclosures, not laboratory tests, so they say what we can evidence rather than that anything is safe.

Best graded hand sanitizer here

  1. 1Dettol Instant Hand Sanitizer 50ml 75 out of 100
  2. 2Seventh Generation Hand Wash Natural Seventh Generation 75 out of 100
  3. 3Aesop Resurrection Aromatique Hand Wash 75 out of 100

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The best non-toxic hand sanitizer, ranked by grade

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Buyer’s guide

What to look for in hand sanitizer, and which brands grade best and worst

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Which hand sanitizer is PFAS-free? Good or Excellent, best-graded first

Dettol Instant Hand Sanitizer 50ml

Dettol

Instant Hand Sanitizer 50ml

75ExcellentPFAS grade
  • Aqueous alcohol-based liquid sanitizer (ethanol, water, glycerin)
  • We found no PFAS statement from the brand
  • Fragrance allergens

5 hazards checked on this product, all on its full breakdown.

Hand Wash Natural Seventh Generation

Seventh Generation

Hand Wash Natural Seventh Generation

75ExcellentPFAS grade
  • water-based surfactants, plant-derived ingredients
  • Fragrance allergens

2 hazards checked on this product, all on its full breakdown.

Aesop Resurrection Aromatique Hand Wash

Aesop

Resurrection Aromatique Hand Wash

75ExcellentPFAS grade
  • aqueous liquid cosmetic formulation (soap/detergent base)
  • We found no PFAS statement from the brand
  • Fragrance allergen sensitization

2 hazards checked on this product, all on its full breakdown.

Aesop Resurrection Rinse-Free Hand Mist

Aesop

Resurrection Rinse-Free Hand Mist

75ExcellentPFAS grade
  • Water, plant extracts, preservatives (standard cosmetic formula)
  • We found no PFAS statement from the brand
  • Preservative sensitization (contact allergen risk)

4 hazards checked on this product, all on its full breakdown.

  • Alcohol gel base (ethanol/isopropyl), aloe vera extract, glycerin
  • We found no PFAS statement from the brand
  • Fragrance allergens and skin sensitivity

4 hazards checked on this product, all on its full breakdown.

Dettol Instant Liquid Hand Sanitiser 200mL

Dettol

Instant Liquid Hand Sanitiser 200mL

75ExcellentPFAS grade
  • Aqueous liquid hand sanitiser (water-based, alcohol)
  • We found no PFAS statement from the brand
  • Alcohol flammability

4 hazards checked on this product, all on its full breakdown.

Dettol Original Instant Hand Sanitizer

Dettol

Original Instant Hand Sanitizer

75ExcellentPFAS grade
  • Aqueous alcohol-based sanitizer liquid (ethanol, water, isopropanol typical formulation)
  • We found no PFAS statement from the brand
  • Skin irritation or sensitization (alcohol, fragrance if present)

4 hazards checked on this product, all on its full breakdown.

Purell Advanced Hand Sanitizer Refreshing Gel

Purell

Advanced Hand Sanitizer Refreshing Gel

75ExcellentPFAS grade
  • ethyl alcohol gel with humectants (aloe, glycerin)
  • We found no PFAS statement from the brand
  • Ethanol skin irritation or sensitization

4 hazards checked on this product, all on its full breakdown.

PURELL Advanced Refreshing Gel Hand Sanitizer

Purell

Advanced Refreshing Gel Hand Sanitizer

75ExcellentPFAS grade
  • aqueous gel (alcohol, water, carbomer, glycerin, fragrance)
  • We found no PFAS statement from the brand
  • Fragrance allergens

2 hazards checked on this product, all on its full breakdown.

Hydrating Antibacterial Hand Mist

Hydrating Antibacterial Hand Mist

75ExcellentPFAS grade
✓ Leaping Bunny
  • Water-based cosmetic spray (alcohol, water, plant extracts, preservatives)
  • Formaldehyde / VOCs

4 hazards checked on this product, all on its full breakdown.

Dettol Instant Disinfectant Hand Sanitizer

Dettol

Instant Disinfectant Hand Sanitizer

75ExcellentPFAS grade
  • Liquid hydroalcoholic hand sanitizer formulation
  • We found no PFAS statement from the brand
  • Fragrance allergens

5 hazards checked on this product, all on its full breakdown.

Aesop Resurrection Rinse-Free Hand Wash

Aesop

Resurrection Rinse-Free Hand Wash

75ExcellentPFAS grade
  • Water-based rinse-free hand wash; surfactants, humectants, botanical extracts
  • We found no PFAS statement from the brand
  • Fragrance allergens (essential oils)

2 hazards checked on this product, all on its full breakdown.

Dettol Sanitizer

Dettol

Sanitizer

75ExcellentPFAS grade
  • aqueous solution (water-based antiseptic liquid)
  • We found no PFAS statement from the brand
  • Contact dermatitis (chloroxylenol and fragrance)

5 hazards checked on this product, all on its full breakdown.

Purell Advanced Gel Hand Sanitizer

Purell

Advanced Gel Hand Sanitizer

75ExcellentPFAS grade
  • Ethyl alcohol gel (typical hand sanitizer base)
  • We found no PFAS statement from the brand
  • Skin irritation and sensitization (fragrance/additives)

4 hazards checked on this product, all on its full breakdown.

  • Water-based gel sanitizer with glycerin moisturizer; plastic bottle
  • BPA & bisphenols

3 hazards checked on this product, all on its full breakdown.

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